Sinner, ranked No 1, will play Russian Daniil Medvedev, the No 5 seed, next.

In the previous rounds of the US Open, the Italian won against American Mackenzie McDonald (2-6, 6-2, 6-1, 6-2), American Alex Michelsen (6-4, 6-0, 6-2) and Australian Christopher O’Connell (6-1, 6-4, 6-2).

Paul, ranked No 14, won against Italian Lorenzo Sonego (6-4, 6-2, 5-7, 6-2), Australian Max Purcell (7-5, 6-0, 1-0 ret.) and Canadian qualifier Gabriel Diallo (6-7 (5), 6-3, 6-1, 7-6 (3)) earlier in the tournament.

New York (Grand Slam), other last 16 results (USTA Billie Jean King National Tennis Center, hard, USD 75.000.000, most recent results first):

• Alex De Minaur (10) beat Jordan Thompson: 6-0, 3-6, 6-3, 7-5
• Daniil Medvedev beat Nuno Borges: 6-0, 6-1, 6-3
• Jack Draper (25) beat Tomas Machac: 6-3, 6-1, 6-2
• Frances Tiafoe (20) beat Alexei Popyrin (28): 6-4, 7-6 (3), 2-6, 6-3
• Alexander Zverev (4) beat Brandon Nakashima: 3-6, 6-1, 6-2, 6-2
• Taylor Fritz (12) beat Casper Ruud (8): 3-6, 6-4, 6-3, 6-2
• Grigor Dimitrov (9) beat Andrey Rublev (6): 6-3, 7-6 (3), 1-6, 3-6, 6-3