The New York Jets fired head coach Robert Saleh on Tuesday after a 2-3 start, which includes back-to-back losses. Aaron Rodgers and the Jets will try to get back on track when they take on the Buffalo Bills in an AFC East showdown on Monday Night Football. New York has struggled in this rivalry in recent years, losing seven of the last 10 meetings against Buffalo. The latest Week 6 NFL odds list the Jets as 2.5-point underdogs at home on Monday Night Football, but should you include New York to pull off the upset in your Week 6 NFL office pool picks?

Elsewhere on the Week 6 NFL schedule, Jordan Love and the Green Bay Packers (-5.5) will host Kyler Murray and the Arizona Cardinals. Will Love lead his team to victory at Lambeau Field, or will the Cardinals pull off another upset for NFL confidence pool picks? Before you make your NFL predictions, you need to see the Week 6 NFL football pool picks from SportsLine’s proven model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 6 of the 2024 NFL season on an incredible 10-2 hot streak on top-rated NFL picks this year. Longer term, it is on a 191-131 roll on top-rated NFL picks that dates back to the 2017 season and a 45-23 roll on top-rated NFL picks since Week 7 of 2022.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Get football picks for every game from a proven NFL model

In Week 6 NFL betting, SportsLine’s advanced computer model, which simulates every NFL game 10,000 times, says the Chicago Bears (-1.5, 44.5) beat the Jacksonville Jaguars in London. Chicago features one of the stingiest defenses in the league, giving up just 294.8 yards per game on average, which ranks seventh in the NFL. The Jaguars, meanwhile, are giving up 393.4 yards per game on defense, which ranks 31st.

Chicago’s offense also seems to be finding its rhythm in recent weeks. The Bears scored 36 points in last week’s victory over the Panthers behind a strong showing from rookie quarterback Caleb Williams. The rookie threw for 304 yards and two touchdowns while also rushing five times for 34 yards. Running back D’Andre Swift has also found his groove after a slow start. Over his last two games, Swift has rushed for 166 yards and two touchdowns on 37 carries. He’s also been effective as a pass catcher, hauling in nine receptions for 119 yards over his last two outings. The Bears are trending in the right direction for those who want to back them with Week 6 NFL pool picks, and the model has Chicago winning in nearly 60% of simulations. See all of SportsLine’s Week 6 NFL predictions here.

How to make Week 6 NFL office pool picks

The model also made the call on every other Week 6 NFL game and has strong picks for potentially close NFL matchups like Buccaneers vs. Saints (+3.5), Lions vs. Cowboys (+3) and Bills vs. Jets (+2.5). It’s also calling for a pair of upsets you won’t want to miss. You can only see all of the model’s NFL pool picks here.

So who should you pick in every Week 6 NFL game, and which upsets will shock the league? Visit SportsLine now to get optimal NFL office pool picks, all from a proven computer model that has returned well over $7,000 since its inception, and find out.