The American Express 2025 is set to get underway on Thursday, Jan. 16, and several players will enter this week’s event confident they can secure the victory. Nick Dunlap made history at The American Express last year, becoming the first amateur to win a PGA Tour event since Phil Mickelson. Dunlap is coming off a top-10 finish at last week’s Sony Open, but should you include him in your The American Express 2025 picks? The 2025 American Express field is loaded with major champions, including Xander Schauffele, Justin Thomas, Wyndham Clark and Jason Day. 

Schauffele, the No. 2 ranked player in the world, is listed as the +700 favorite according to the latest 2025 American Express odds. He’s followed by Thomas (+1200), Sungjae Im (+1400), Patrick Cantlay (+2000) and Sam Burns (+2000) on the PGA odds board. Before locking in your The American Express 2025 picks, be sure to see the golf predictions and projected leaderboard from the proven computer model at SportsLine.

SportsLine’s proprietary model, built by DFS pro Mike McClure, has been red-hot since the PGA Tour resumed in June 2020. In fact, the model is up more than $9,500 on its best bets since the restart, nailing tournament after tournament.

This same model has also nailed a whopping 13 majors entering the weekend, including the 2024 Masters — its third Masters in a row — and last year’s PGA Championship and U.S. Open. Anyone who has followed its sports betting picks could have seen massive returns on betting apps like FanDuel, DraftKings and Fanatics. 

Now that The American Express 2025 field is locked in, SportsLine simulated the tournament 10,000 times, and the results were surprising. Head to SportsLine now to see the projected leaderboard.

The American Express 2025 predictions 

One major surprise the model is calling for at the 2025 American Express: Im, a two-time PGA Tour champion and one of the top favorites, stumbles this week and barely cracks the top 10. Im got off to a fast start in 2025, securing a third-place finish at The Sentry in Hawaii. 

However, Im has failed to crack the top 10 in each of his last four starts at this event. He was also extremely inconsistent with his irons last season, ranking 99th in strokes gained: approach to green (0.054) and 145th in greens in regulation percentage (65.13%). He’s not a strong pick to win it all and there are far better values in The American Express 2025 field. See who else to fade here. 

Another surprise: J.J. Spaun, a 40-1 longshot, makes a strong run at the title. He has a much better chance to win it all than his odds imply, so he’s a target for anyone looking for a huge payday.

Spaun is coming off a T-3 showing at last week’s Sony Open and has all the tools needed to be in the mix again this week in California. The 34-year-old currently ranks second in strokes gained: approach to green (2.025), fourth in scoring average (66.25) and eighth in greens in regulation percentage (84.72%). He also ranks inside the top 50 in putting average (1.721) and strokes gained: putting (0.374). Those impressive stats, plus his long odds, make him a strong value pick for your 2025 American Express bets. See who else to pick here. 

How to make 2025 American Express picks

The model is also targeting three other golfers with odds of 40-1 or longer who will make a strong run at the title. Anyone who backs these longshots could hit it big. You can only see the model’s picks here.

Who will win The American Express 2025, and which longshots will stun the golfing world? Check out the 2025 American Express odds below and then visit SportsLine to see the projected leaderboard, all from the model that’s nailed 13 golf majors, including the last three Masters and three majors in 2024.

The American Express odds, favorites 

Get full 2025 American Express picks, best bets and predictions here. 

Xander Schauffele +700
Justin Thomas +1200
Sungjae Im +1400
Patrick Cantlay +2000
Sam Burns +2000
Tony Finau +2500
Tom Kim +3300
Wyndham Clark +3500
Si Woo Kim +3500
Max Greyserman +4000
J.J. Spaun +4000
Harry Hall +4500
Kurt Kitayama +4500
Cameron Young +4500
Davis Thompson +5000
Nick Dunlap +5500
Brian Harman +5500
Eric Cole +5500
Will Zalatoris +6000
Nicolas Echavarria +6000
Patrick Fishburn +6000
Ben Griffin +7000
Denny Mccarthy +7000
Tom Hoge +7000
J.T. Poston +7000
Sepp Straka +7500
Nick Taylor +7500
Jason Day +8000
Keith Mitchell +8000
Cameron Davis +8000
Adam Hadwin +8000
Daniel Berger +8000
Michael Thorbjornsen +8000
Christiaan Bezuidenhout +9000
Kevin Yu +9000
Rickie Fowler +9000
Beau Hossler +9000
Bud Cauley +9000
Jhonattan Vegas +9000
Lucas Glover +10000
Lee Hodges +10000
Andrew Novak +10000
Mac Meissner +11000
Alex Smalley +11000
Doug Ghim +11000
Michael Kim +11000
Billy Horschel +11000
Erik Van Rooyen +12000
Jesper Svensson +12000
Harris English +12000
Patrick Rodgers +12000
Jackson Suber +12000
Samuel Stevens +12000
Andrew Putnam +12000
Mark Hubbard +12000
Chris Kirk +12000
Joe Highsmith +15000
Rico Hoey +15000
Chan Kim +15000
Mackenzie Hughes +15000
Taylor Moore +15000
Matthias Schmid +15000